ABOUT GENERATION HOPE

 

Generation Hope is a documentary series in production that follows families, clinicians, and researchers on the front lines of gene therapy. We document the real-world journeys of children and families living with Phelan-McDermid, Rett, STXBP1 and Angelman syndromes, and track the gene-therapy trials now underway. Each family story is paired with deep, unfiltered conversations with the scientists and clinicians who are turning decades of research into potentially life-changing treatments.

We believe this generation of children could be the first to benefit from cures and transformative therapies for conditions once thought untreatable. Generation Hope explains the science in human terms, shows what progress looks like in lived experience, and provides a reliable resource for patients, clinicians, and supporters.

Website - Interviews - docuseries

GENErationHope.co

The Documentary Series

The Interview Series

 GenerationHope.co is a resource for families and researchers affected by rare genetic disorders. We publish timely news, expert interviews, research summaries and practical resources to help you follow advances in gene therapy and what they mean for real lives.


The website will have a searchable knowledge base of everything discussed in t

 GenerationHope.co is a resource for families and researchers affected by rare genetic disorders. We publish timely news, expert interviews, research summaries and practical resources to help you follow advances in gene therapy and what they mean for real lives.


The website will have a searchable knowledge base of everything discussed in the interviews and make this available to the research community.
 

The Interview Series

The Documentary Series

The Interview Series

 

The Interview Series is the companion to our  docuseries — a monthly program of long-form, unedited conversations with the people shaping the future of genetic medicine.  

We interview the leading scientists and researchers and advocates in Gene Therapy. 


Next Month's Feature Interview:

Wendy Chung - 

The Documentary Series

The Documentary Series

The Documentary Series

Generation Hope is a documentary series currently in production  that follows families, clinicians, and researchers on the front lines of gene therapy. We document the real-world journeys of children and their families, and pair those stories with deep, unfiltered conversations with the scientists and clinicians working to turn decades of research into life-changing therapies.


Dr. Alex Kolevzon on Gene Therapy, SHANK3 & the Future

Monica Coenraads, CEO Rett Syndrome Research Trust

Monica Coenraads, founder and CEO of the Rett Syndrome Research Trust (RSRT), has led the charge to cure Rett Syndrome—raising over $123 million and driving multiple gene therapy programs now in clinical trials.  In this in-depth conversation, Monica shares her personal journey from her daughter Chelsea’s diagnosis to building one of the world’s most impactful rare disease research organizations. She explains the evolution of Rett research—from the discovery of MECP2 to today’s cutting-edge genetic medicines including gene therapy, base and prime editing, and RNA trans-splicing.

Dr. Alex Kolevzon

In this wide-ranging interview, Dr. Alex Kolevzon (Mount Sinai) sits down to discuss the science, the trials, and the human side of gene therapy for rare neurodevelopmental disorders.

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